The player has entered Sander Cohen's personal quarters.

The player has taken a picture of Sander Cohen's corpse

The player has become a Big Daddy.

The player has defeated Atlas

The player has broken Fontaine's mind control

The player has defeated Andrew Ryan

The player has completed Sander Cohen's great masterpiece

The player has restored the forests of Arcadia

Find every audio diary.

Collect or Invent 53 Tonics in the Physical, Engineering and Combat tracks.

Acquire all upgrades for all weapons.

Fully upgrade five weapons.

Successfully invent at least 100 items.

Fully upgrade four weapons.

Max out all possible research.

Hit the jackpot at a slot machine

Complete the game on the hardest difficulty setting.

Fully research the Nitro Splicer.

Fully research the Little Sister.

Take at least one photo in every research group.

Fully research the Spider Splicer.

Complete the game without harvesting any Little Sisters.

Purchased every slot in all four Plasmid and Tonic tracks

Either Harvest or Rescue every Little Sister in the game

Fully research the Rosie.

Fully upgrade three weapons.

Fully research the Bouncer.

Successfully invented all possible ammo types.

Fully research the Houdini Splicer.

Fully upgrade two weapons.

Fully upgrade one weapon.

Purchased every slot in one of the Plasmid or Tonic tracks

Fully research the Thuggish Splicer.

Fully research the Leadhead Splicer.

Successfully invent at least one item.

he player has successfully completed 50 hacks.

The player has acquired at least one weapon upgrade.

The player has defeated Peach Wilkins

The player has successfully hacked a security camera.

The player has taken at least one Research Photo of a Splicer.

The player has taken a Research Photo of the highest grade.

The player has purchased one slot in any Plasmid or Tonic track

The player has successfully hacked a safe.

The player has defeated the crazed Dr. Steinman

The player has successfully hacked a vending machine.

The player has successfully hacked a turret.

The player has successfully hacked a security bot.

The player has performed at least one successful hack.

The player has successfully completed the Welcome To Rapture Level.

The player has shocked an enemy in the water.

Complete the game on Hard difficulty without using a Vita-Chamber