Published on January 2, 2009 Just beat the game on easy with the vita chambers turned off, this will make it simple to beat the game with out dieing.
once you have beat the boss on easy select continue and as soon as the fight starts change the game difficulty to hard and beat him for the Brass Balls and the Seriously Good At This achievement.
Published on October 27, 2008 Go to options and turn off Vita Chamber, then, complete the game on Hard. SAVE AFTER EVERY BOOS BATTLE, ENCOUNTER WITH MANY ENEMIES, WHEN ABOUT TO DIE, AFTER DEFEATING BIG DADDYS.